Antidiabetic activity of stem extracts of Tinospora cordifolia on streptozotocin induced diabetic Wistar rat


Mohammed Abdullah, Y. Al Eryani and Prakash R. Naik*
Endocrinology Laboratory, Department of Zoology, University of Mysore, Mysore - 570 006 (India)

Download this article as:  PDF

ABSTRACT:

The aim of the present experiment was to evaluate therapeutic efficacy of stem extracts of Tinospora cordifolia on diabetes induced animal model Wistar rat. Experimental animals were grouped in to control (I), control with T. cordifolia stem extract (II) control diabetic (III) and Diabetic group with T. cordifolia stem extract treated with 100 mg/kg body weight for 35 day (IV). Blood glucose, glycosylated haemoglobin, triglycerides, cholesterol, LDL, VLDL, HDL and blood urea were measured at the beginning and termination of experiments. Blood glucose and other parameters were elevated in diabetic group. Elevated levels were significantly reduced in alleviating the diabetic condition after treatment with stem extract of T. cordifolia.

KEYWORDS:

Diabetic rat; Tinospora cordifolia; Glycosylated haemoglobin; Cholesterol; HDL; LDL; VLDL

Visited 285 times, 1 visit(s) today
Article Publishing History
Received on: August 29, 2007
Accepted on: October 11, 2007


Share

FOLLOW US ON:

facebook Twitter Mendeley LinkedIn


SEARCH WEBSITE


MEMBER OF

Logo-image


JOURNAL ARCHIVED IN

Logo-image


Visited 285 times, 1 visit(s) today