Anti-ulcerogenic effects of methanolic extract of unripe fruits of Ficus racemosa Linn.

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The anti-ulcerogenic effect of unripe fruits of Ficus racemosa Linn commonly known as Gular in Hindi was examined in gastric ulcer models induced by aspirin (200 mg/kg) and cold restrains stress. The 50% ehanolic extract of Ficus racemosa were given orally at the doses of 100 mg/kg (35.78 % and 28.82%, P<0.01), 200 mg/kg (58.33 % and 48.03%, P<0.01) and 400 mg/kg (82.84 % and 76.41%, P<0.001) and sucralfate (Standard drug) at a dose of 250mg/kg (78.43 % and 69.86%, P<0.001) for 5 days, respectively. Unripe fruits of F. racemosa produced significant anti-ulcer activity in all the experimental gastric ulcer models.

Anti-ulcer; Aspirin; Cold-restrain stress; Ficus racemosa