An improved industrial process for synthesis of HMG-CoA reductase inhibitor Pitavastatin
1Department of Research and Development, MSN Laboratories Limited Survey No 317 and 323, Rudraram, Patancheru, Medak - 502 329 (India).
2Department of Chemistry, P.G. College of Science, Saifabad, Hyderabad (India).
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An highly efficient cost effective, eco-friendly, commercially viable, convergent synthesis for the manufacturing of Pitavastatin, a HMG-CoA reductase inhibitor, has been developed.
KEYWORDS:Pitavastatin; HMG-CoA reductase inhibitor; E-alkene; syn-diol; Wittig-Horner-Emmons Coupling
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Article Publishing History
Received on: August 13, 2007
Accepted on: October 09, 2007
Accepted on: October 09, 2007
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