Serum antioxidant enzyme levels and lipid peroxidation rate in type-ii diabetes

K. S. C. Bose; B.K. Agrawal; Anil Baran Choudhury; S. Das

Article | Open Access

Serum antioxidant enzyme levels and lipid peroxidation rate in type-ii diabetes

K. S. C. bose¹*, B. K. Agrawal², Anil Baran Choudhury³ and S. Das⁴

¹Department of biochemistry, people’s College of Medical Sciences and Research Centre, bypass road, bhanpur, Bhopal- 462 010 (India.) ²Department of Biochemistry, Gandhi Medical College, Bhopal. (India) ³Department of Biochemistry, People’s Medical College, bhopal (India) ⁴Department of Pharmacology, Peoples Medical College, bhopal (India)

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ABSTRACT:

Oxidative stress induced by reactive oxygen species (ROS), which are generated due to hyperglycemia may involve in the development of complications in Diabetes. So the aim of this study is evaluate the levels of serum antioxidant enzymes and lipid peroxidation rate in Type-II Diabetes. In this study we observed significantly higher lipid peroxidation (p <0.001) in comparison to normal control and at the same time significantly lower activity of serum antioxidant enzymes were observed in diabetic group (p<0.001) when compared to control group.

KEYWORDS:

Free radicals; oxidative stress; antioxidant enzymes; type-II Diabetes

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Article Publishing History

Received on: 05/04/2007