Physicochemical characterisation and antifungal, cns depressant activity of certain Ethnomedicinal plants of Tripura state, India

M. Datta Choudhury; R. Choudhury; B. De; S.B. Paul3

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Physicochemical characterisation and antifungal, cns depressant activity of certain Ethnomedicinal plants of Tripura state, India

M. Datta Choudhury¹*, R. Choudhury², B. De³ and S. B. Paul⁴

¹Department of Life Science, Assam University, Airongmara, Dargakona, Silchar, Cachar, Assam - 788 011 (India) ²M.T.B. Girls’ H. S. School, Agartala, Tripura - 799 001(India) ³Regional Institute of Pharmaceutical Science And Technology, Tripura - 799006 (India) ⁴Department of Chemistry, Assam University, Silchar, Assam - 788 011 (India)

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ABSTRACT:

Methanolic extract of edible parts of certain ethno medicinal plants(10 Nos.), growing in state Tripura, India, which are used by tribal people, were physicochemically characterized and screened for antifungal activity against Candida albicans and also for CNS depressant property in mice. It was found that extracts were able to exhibit antifungal activity except 03 extracts. Among them, extract of I. aquatica showed zone of inhibition 1.6 cm, which was nearer to the effect of standard. Extracts of S. torvum and L. spinosa showed CNS depressant property in 100mg/kg body weight comparable to the effect of standard in 5mg/kg body weight.

KEYWORDS:

Edible parts; Tribal; Physicochemical; Candida albicans; CNS depressant

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Received on: 08/05/2007