Novel Spectrophotometric Methods for The Determination of Ambroxol Hydrochloride


T. Sathish1, U. Kiran Babu2, K. Kishore Kumar3, S. Sujatha4 and Ch. Balasekhar Reddy5
1Department of Biotechnology, Mallareddy College of Engineering, Secunderabad - 500 014 (India) 2Department of Biotechnology, Godavari Institute of Technology, Rajamendry (India) 3Department of Chemical Engineering, Andhra University, Visakhapatnam – 530 003 (India) 4Department of Pharmaceutical Sciences, Mallareddy College of Pharmacy, Secunderabad - 500 014(India) 5Department of Pharmaceutical Sciences, G. Pulla Reddy College of Pharmacy, Hyderabad-500 028 (India)

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ABSTRACT:

Simple, accurate, rapid and sensitive spectrophotometric methods have been reported for the estimation of Ambroxol using, (I) 3-methyl 2 benzo thiazoline hydrazine hydrochloride(MBTH) in the presence of cerric- ammonium sulphate and (II) 3 methyl 2 benzothiazoline hydrazine hydrochloride(MBTH) in the presence of Ferric chloride. The violet colour chromogens were formed and these were measured at wavelength of maximum absorption 575nm against reagent blanks.

KEYWORDS:

Ambroxol hydrochloride,;cerric ammonium sulphate; spectrophotometer; Beer’s Law

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Article Publishing History
Received on: 10/10/2005


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