eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-05-07 9 2 http://dx.doi.org/10.13005/bbra/1046 10008 article Andrew C. Nwaka 1 Peter N. Uzoegwu 2 Department Of Biochemistry, Anambra State University, Uli, Nigeria. Tropical Diseases Research Unit, Department of Biochemistry, University of Nigeria, Nsukka, Nigeria. In this study, the effect of soyabean supplemented diet on serum protein level and body weight of diabetic rats were evaluated in a total of 32 rats weighing 150-250 grams. The rats were separated into four groups of eight rats each. The groups were as follows: A- Rats fed on rat feed, B-rats fed on rat feed and soyabean meal, C-diabetes-induced rats fed on rat feed and D-diabetes induced rats fed on rat feed and soyabean meal. The rats were fed for 28days, while their body weights were measured at 7 days intervals using electronic metler weighing balance. At the end of the 28days, the rats were bled and sera obtained used to determine serum albumin, globulin and total protein using standard biochemical methods. The results of this study indicated that the mean serum total protein, albumin and globulin concentrations of the diabetic rats fed on normal rat feed (group C) were significantly lower (P<0.5) than those of the control (Group A) and those of diabetic rats fed on soyabean supplemented diet (Group D). There was no significant difference (P>0.05) observed between the mean serum total protein, albumin and globulin levels of diabetic rats fed on soyabean supplemented diet (group D) when compared to those of the control (Group A i.e. rats fed on normal rat fed on normal rat feed). The result of the mean percentage changes in body weight on the first, second and third week of the study indicated significant reduction (P<0.05) in body weight of diabetic rats fed on normal feed when compared to that of the control (Group A), while there was no significant difference (P>0.05) observed in the mean percentage change in body weight of diabetic rats fed on soyabean supplemented diet (Group D) when compared to that of the control, (Group A). https://www.biotech-asia.org/vol9no2/effect-of-soyabean-diet-on-body-weight-and-serum-protein-level-of-alloxan-induced-diabetic-rats/ Diabetes Mellitus; Serum Protein; Body Weight and Soyabean.