eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-05-07 8 2 825 828 9812 article N. A. Tambe `1 C. J. Chandekar 2 Department of Biotechnology, Shri Shivaji Science College, Nagpur (India). Co-ordinator, Biotechnology Department, Shivaji Science College, Nagpur (India). Riboflavin is a yellow, water soluble solid which plays an important role in growth and normal health of many living organisms as well as man. Aspergillus terreus was used for the production of riboflavin which was markedly affected by the composition of the culture medium, incubation period and agitation speed. The growth and production rate of vitamin was high by using shaked flask method. Maximal productivity (1044mg/L) was achieved when fungus was allowed to grow on synthetic medium fortified with glycine, oleic acid and ferric chloride. The used media at pH 6 and agitation speed at 250 rpm showed a good productivity rate for riboflavin in supplemented medium rather than medium containing no additives. https://www.biotech-asia.org/vol8no2/production-of-riboflavin-by-local-isolates-of-aspergillus-terreus/ Riboflavin; Aspergillus terreus; human health