eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-05-05 8 2 435 438 9250 article Manal A. Al Sheddi 1 Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Many interesting histopathological changes may be seen in association with nevi, such as amyloid, nodular myxoid changes, folliculitis, granular cell changes and ossification. We report unusual case of osseous metaplasia within an intradermal melanocytic nevus, osteo-nevus of Nanta. Oral and Maxillofacial pathologist should be aware of this rare entity as they might receive skin biopsy from facial and perioral regions. The possible pathogenesis hypotheses have been discussed briefly. https://www.biotech-asia.org/vol8no2/osteo-nevus-of-nanta-osseous-metaplasia-in-an-intradermal-melanocytic-nevus-case-report-of-an-uncommon-phenomenon/ Osteo-Nevus of Nanta; Osseous Metaplasia; Intradermal Melanocytic Nevus