eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-05-05 8 1 277 282 9349 article G. A. Borker 1 J. M. Dalal 2 N. S. Kulkarni 2 Department of Biotechnology, Vivekanand Science College, Vivekanand Nagar, Hiwara Ashram, Tq. Mehkar, Dist: Buldana - 443 301 (India). Microbiology Research Laboratory, P.G. Department of Microbiology, R.A.College, Washim - 444 505 (India). The aim of this investigation was to elucidate the potential of Moringa oleifera seeds for antimicrobial activity and water purification ability. Ethanolic extracts were used for the assessment of the antimicrobial activity against S. aureus, B. Subtilis, E. coli. P. aeruginosa, and S. typhi and minimum inhibitory concentration (MIC) was also determined. The sensitivity-resistance pattern was found to be S. aureus (9.0 mm),B. subtilis (7.3 mm), P. aeruginosa (7.2 mm) and E.coli (6.8 mm) and S. typhi (4.5 mm) at 50 mg/ml ethanolic seed extract concentration. MIC values ranged from 10-50 μg/ml. The bacteriological quality of drinking water sample was determined by MPN technique. The seed extract treatment brings about significant reductions in the reductions MPN values over control. Present studies suggest the use of Moringa oleifera seeds as an economic and ecofriendly alternative to the chemical coagulant in view of water purification and management of water-borne diseases. https://www.biotech-asia.org/vol8no1/evaluation-of-ethanolic-seed-extract-of-moringa-oleifera-for-antimicrobial-profile-and-water-treatment/ Moringa oleifera; ethanolic seed extract; coagulant; antibacterial activity water purification