eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-04-15 6 1 189 195 8093 article V. Suseela 1 V. K. Gopalakrishnan 1 D. Chandrapraba 2 Department of Biochemistry, Karpagam University, Coimbatore - 641 021 (India). Department of Biochemistry, Sree Narayanaya Guru college, Coimbatore - 641 021 (India). Antioxidant potential of leaves of Artemisia nilagirica was studied using different in vitro models like 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothizoline-6-sulphonate) (ABTS), nitric oxide, superoxide, hydroxyl radical and lipid peroxidation. The ethanol extract showed maximum scavenging activity (89.06%) of ABTS radical followed by the scavenging of DPPH radical (84.94%) and superoxide radical (79.69%) respectively. Total antioxidant capacity was found to be 61.3 mg ascorbic acid equivalents at 500μg/ml extract concentration. However, the extract showed only moderate lipid peroxidation inhibition activity. Total phenols and flavonoids were found to be 69.71 + 1.7 mg Gallic acid equivalents/g of dry material and 28.41 + 0.6 mg Quercetin equivalents/g of dry material respectively. These results suggest that phenolics and flavonoids in the leaves provide substantial antioxidant activity. https://www.biotech-asia.org/vol6no1/evaluation-of-free-radical-scavenging-potential-of-ethanolic-extract-of-artemisia-nilagirica-clarke-pamp-leaves/ Artemisia nilagirica; free radical; in vitro studies