eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-04-23 5 2 841 844 8503 article N.G. Sutar 1 U.N. Sutar, 1 Y.P. Sharma 1 I.K. Shaikh 1 S.S. Kshirsagar 1 S.N.D. College of Pharmacy, Babhulaon, Tal- Yeola, District Nashik (India). Achyranthus aspera Linn. leaves have antimicrobial, anti-inflammatory, venereal affection, analgesic, antipyretic activity, in treatment of eyes, arthritis as antiirlityetc. Methanolic extract of leaves of Achyranthus aspera Linn. reported as analgesic activity but leaves till not reported, the effect of alcoholic extract and its various fraction as Petroleum ether, Ethyl acetate, Diethyl ether, n-Butanol were tested for phytochemically which contain glycosides, flavonoids, tannins, amino acids. As analgesic activity by using hot plate method and antipyretic by using brewers yeast induced method and compare with Aspirin as a standard in a dose of [25mg/kg] for analgesic and [125mg/kg] for antipyretic effect. https://www.biotech-asia.org/vol5no2/phytochemical-investigation-and-pharmacological-screening-of-leaves-of-achyranthus-aspera-linn-as-analgesic-and-antipyretic/ Leavess of Achyranthus aspera Linn; Analgesic activity by hot plate