eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-04-04 5 2 757 762 7553 article Pankaj Kumar Sharma 1 Arun Kumar 1 Meenakshi Bajpai 1 Monika Sachdeva 1 Pradeep Kumar1 2 College of Pharmaceutical Sciences, Raj Kumar Goel Institute of Technology, Ghaziabad (India). Department of Pharmaceutical Analysis, PES College of Pharmacy, Bangalore (India). Received on : September 15, 2008 Ocular inserts of Ciprofloxacin hydrochloride using Gelrite, HPMC, PVP and Carbopol were prepared by surface casting method and evaluated for uniformity of thickness, weight, drug content, surface pH, percent moisture absorption , percent moisture loss and in vitro release study. It can be concluded from the study that gelrite based ocular inserts of Ciprofloxacin hydrochloride shows constant release upto 6 hrs and can be effectively used for sustained topical ocular delivery. https://www.biotech-asia.org/vol5no2/formulationoptimization-and-evaluation-of-ocular-inserts-of-ciprofloxacin-hydrochloride/ Gelrite; HPMC; PVP; Carbopol; Ciprofloxacin hydrochloride; ocular insert