eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-03-10 5 1 479 481 7065 article UV-Spectrophotometric Determination of Alfuzosin Hydrochloride in Bulk and Tablets M.Sugumaran 1 P. Suresh 1 T. Vetrichelvan 1 Adhiparasakthi College of Pharmacy, Melmaruvathur - 603 319 (India) A simple, rapid, sensitive and accurate UV- spectrophotometric method has been developed for estimation of alfuzosin hydrochloride from pharmaceutical formulations. In 0.1M NaOH, alfuzosin hydrochloride showed absorbance maxima at 350 nm. Linearity was observed in the concentration range of 10-30 μg/ml (r2=0.999914). The amount of drug estimated from the formulation was found to be in the good agreement with label claim. The recovery studies were carried out at three different levels i.e. at 50%, 70% and 90%. The method was validated statistically. https://www.biotech-asia.org/vol5no1/uv-spectrophotometric-determination-of-alfuzosin-hydrochloride-in-bulk-and-tablets/

UV- spectrophotometric method; Alfuzosin hydrochloride