eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-02-10 5 1 261 268 6632 article P. Uma Devi 1 P. Chinnaswamy 2 S. Murugan 3 S. Selvi 1 School of Biotechnology, Karunya University, Coimbatore - 14 (India) Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam (India) Post Graduate and Research Department of Biochemistry and Microbiology, Dr.N.G.P.Arts and Science College, Coimbatore (India) To determine changes of plasma trace elements levels (zinc, copper, magnesium, and iron) in schizophrenic patients with positive, negative and cognitive symptoms. The observations in the present study suggest that alterations in essential trace elements Mn, Cu, Zn, Se and Fe may play a role in the pathogenesis of schizophrenia. Supplementation of trace minerals -rich diet, which are thought to increase the antioxidant system activity, can be useful and effective in the treatment of the schizophrenia. https://www.biotech-asia.org/vol5no1/plasma-levels-of-trace-elements-in-patients-with-different-symptoms-of-schizophrenia/ Schizophrenia; Trace elements; Flame atomic absorption spectroscopy; clinical significance