eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-03-09 5 1 461 463 7022 article R. A. Fursule 1 D. K. Rupala 1 Md. Mujeeb Gulzar Khan 1 A. A. Shirkhedkar 1 S. J. Surana 1 Department of Pharmaceutical Chemistry, R.C. Patel College of Pharmacy, Karwand Naka, Shirpur, Dist: Dhule - 425 405 (India) Simple, rapid, sensitive and accurate UV- Spectrophotometric methods have been developed for estimation of Quetiapine fumarate and Cilostazol in pharmaceutical formulation. In water, QTF showed absorbance maxima at 290 nm. In acetonitrile (30% v/v) CLZ showed maximum absorbance at 258 nm. Linearity was observed in the concentration range 6 - 54 μg/ml (r2= 0.9999) for QTF and 3 - 21 μg/mL (r2 = 0.9993) for CLZ. Amounts of drug estimated from the tablet formulations were in good agreement with label claim. Both the methods were validated statistically and by recovery studies. https://www.biotech-asia.org/vol5no1/determination-of-quetiapine-fumarate-and-cilostazol-in-bulk-and-tablet-by-uv-spectrophotometry/ UV- Spectrophotometry; Quetiapine fumarate; Cilostazol