eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-03-04 5 1 389 39 6918 article R. Senthil Kumar 1 R. Manivannan 1 A. Balasubramaniam 1 R. Natarajan 1 B. Rajkapoor 2 Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Elayampalayam, Tiruchengodu- 637 205 (India) Department of Pharmacology, St Johns Pharmacy College, No 6, 9th Cross, 2nd Main, Vijayanagar 2nd Stage, Bangalore - 560 104 (India) Anticancer activity of ethanol extract of Pandanus fascicularis Lam. (EPF) was studied in mice. The anticancer activity of EPF was evaluated against Ehrlich Ascites Carcinoma (EAC) tumor model on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPF increased the survival time and decreased the average body weight of the tumor bearing mice. After 14 days of inoculation, EPF is able to reverse the changes in the haemotological parameters, protein and PCV consequent to tumor inoculation. Oral administration of EPF was effective in reducing solid tumor mass development induced by EAC cells. The results shows EPF possess significant anticancer activity on dose dependent manner. https://www.biotech-asia.org/vol5no1/anticancer-activity-of-pandanus-fascicularis-lam/ Ehrlich Ascites Carcinoma; Haematological parameters; Pandanus fascicularis