eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-01-07 2 1 33 36 3418 article A. Olonisakin 1 M.O. Aremu 1 E. A. Omonigbehin 2 Department of Chemistry, Nasarawa state University, P.M.B. 1022, Keffi, Nasarawa State Nigeria Institute of Medical Research, P.M.B. 1013, Yaba, Lagos (Nigeria) Phytochemical and antimicrobial investigation of Phyllantus amarus was carried out. Phyllantus amarus (eyin-olobe) family Euphorbiaceae were extracted with hexane and methanol using sohxlet extractor also water extract was carried out. The extracts were screened for the classes of organic compounds present and antimicrobial activity was carried out using five bacteria including Klebsiella, Helicobacter pylori, Pseudomonas auruginosa, Escherichia coli and Shigella. Phytochemical tests showed that aqueous and methanolic extracts of Phyllantus amarus contained flavonoids, tannins, saponins, glycosides and cardiac glycosides, while hexane extract does not contain any of these compounds. The methanolic and aqueous extracts were found to be effective against the tested organisms while the hexane extract was observed to show negative. https://www.biotech-asia.org/vol2no1/phytochemical-and-antimicrobial-investigations-of-extractive-from-phyllantus-amarus/ Antimicrobial activity; crude extract; Phyllanthus amarus