eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2026-03-30 23 1 141 150 10.13005/bbra/3486 58608 article Sagar Kashinath Khokale 1 Harshali Raosaheb Ahire 1 Mohit Madhukar Jadhav 2 Chetana Krushnaro Shinde 1 Sakshi Rajendra Chaudhari 3 Department of Pharmaceutics, Sandip Institute of Pharmaceutical Sciences, Nashik, India. Department of Pharmaceutics, Siddhi’s Institute of Pharmaceutical Sciences, Kalyan, India. Department of Pharmaceutics, Mahavir Institute of Pharmacy, Nashik, India. In this study, we will review the potential of niosomal formulation. The utilization of niosomes is progressively gaining momentum owing to their eco-friendliness, cost-effectiveness in materials and production, Viability for manufacturing on a large scale, and simplified maintenance compared to other delivery systems. Niosomes play a crucial role in medication delivery systems due to their nonionic nature, enabling controlled release and precise targeting for treating skin conditions and a range of other diseases. The review methodology encompassed several key phases: formulating the research query, conducting preliminary investigations, devising search strategies, database exploration, establishing exclusion and inclusion criteria, author concurrence, selection of titles and abstracts, documenting the number of selected data, full-text retrieval, and scrutiny, supplementary manual searches across platforms like Google Scholar, Scopus, Mdpi, and ResearchGate, data extraction and quality assessment, dual verification of data, revising, and eventual submission. A comprehensive analysis revealed a noteworthy enhancement in the aesthetic appeal of cosmetic products formulated using niosomal technology. https://www.biotech-asia.org/vol23no1/review-on-the-use-of-niosomes-as-a-potential-formulation-for-skin-health/ Amphiphilic; Controlled release; Cosmetics; Encapsulation; Nanotechnology; Niosomal formulation; Niosomes; Skin penetration; Transdermal administration