eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2026-03-30 23 1 190 203 10.13005/bbra/3490 58228 article Kajari Roy 1 Nandan Bhattacharyya 2 Department of Agriculture, Jharkhand Rai University (JRU), Raja Ulatu, Jharkhand, India. Department of Biotechnology, Panskura Banamali College (Autonomous), Panskura, West Bengal, India. Heavy metal contamination represents a persistent global environmental challenge due to its non-biodegradable nature, ecological toxicity, and severe risks to human health. Microbial bioremediation has emerged as a sustainable alternative to conventional physicochemical methods, with Lysinibacillus species gaining increasing attention for their exceptional metal tolerance and detoxification capabilities. The present study provides a comprehensive bibliometric and network-based evaluation of global research trends related to Lysinibacillus-mediated bioremediation of heavy metals. Bibliometric data were retrieved from the Dimensions AI database and analysed using VOSviewer to identify publication trends, leading countries, institutions, journals, and collaborative networks. To complement this analysis, a curated gene-species interaction network was constructed and analysed in Cytoscape to elucidate functional relationships among key microbial taxa and metal-resistance genes. The results reveal a sharp increase in research output since 2017, with India, China, and the United States emerging as major contributors. Network analysis identified Lysinibacillus sphaericus as a central and multifunctional node strongly associated with critical metal-resistance genes such as merA, arsB, and czcC, as well as pathways involved in organic pollutant degradation. The integrated findings highlight the ecological and biotechnological significance of Lysinibacillus, particularly L. sphaericus, as a keystone organism for designing effective synthetic microbial consortia for complex heavy metal remediation strategies. https://www.biotech-asia.org/vol23no1/investigating-the-ability-of-lysinibacillus-spp-to-detoxify-heavy-metals-using-bibliometric-and-network-analysis/ Bibliometric; Bioremediation; Consortia; Gene-species interaction network; Heavy metal; Lysinibacillus