eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2025-09-30 22 3 1042 1053 10.13005/bbra/3422 56542 article Erram Nagendram 1 Departnent of Biochemistry, University College of Science, Osmania University, Hyderabad, Telangana State, India. Due of maize's moderate sensitivity to salt stress, soil salinity poses a major danger to its global output. Developing solutions for enhanced performance in saline circumstances may be aided by researching how maize plants react to salt stress, resistance mechanisms, and management alternatives. We used maize hybrids (NK6240, M900Gold) (Zea mays L.) to check their yield concerning soil salt stress condition. Using 2D polyacrylamide gel electrophoresis, biochemical and protein patterns were examined following the application of salt stress to developing plants and the spots of interest were subjected to Mass spectrometry. As per our research outcomes among differentially expressed proteins, chosen seven spots of interest for comparative analysis and Among these three proteins are up -regulated and remaining four proteins are down-regulated. Thus concluded both maize hybrids given response and the effect of soil saline stress conditions of both varieties (NK6240, M900Gold). https://www.biotech-asia.org/vol22no3/proteomic-and-biochemical-analysis-of-maize-hybrids-zea-mays-l-induced-by-salt-stress/ IEF; MS; MALDI-TOF; Maize; Salt Stress