eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2025-06-25 22 2 425 434 10.13005/bbra/3373 55698 article Vangala Tulasi Iswariya 1 Anees Mohammad 1 Kota Sanihitha 1 Neerudi Sai kiran 1 Tadikonda Rama Rao 1 Department of Pharmaceutics, CMR College of pharmacy, Medchal, Hyderabad, Telangana, India,. The current study attempts to create and assess an herbal gel with natural elements that has a therapeutic impact without causing any adverse effects. Protectants, antiseptics, and antimicrobials are just a few of the uses for it topically. The term "herbal formulations" refers to a dosage form that contains one or more herbs or processed herbs in precise amounts to offer particular nutritional and cosmetic benefits intended for use in the diagnosis, treatment, and mitigation of human or animal diseases as well as in modifying the physiology or structure of subjects. Carbapol was used to make the gel, glycerine as softening agent, and natural turmeric. No preservative was added Since they are more compatible with the human body, and have less adverse effects. Herbs have been shown to aid in the treatment of a number of skin conditions, including dermatitis, rashes, allergies, psoriasis, and eczema. Antiseptic, antibacterial, anti-inflammatory, anti-aging, anti-acne, wound healing, anti-ulcer, anti-tumor, antimalarial, antipyretic, the list goes on. The prepared herbal gel was found to be safe by a variety of evaluation investigations, including stability, patch, microbiological, pH, and irritant tests. Herbal gel formulation has a broad scope encompassing topical applications for a variety of purposes like wound healing, pain relief, and skin protection. https://www.biotech-asia.org/vol22no2/multipurpose-topical-herbal-gel-a-review-article/ Aloe; Dermatitis; Eczema.; Herbal gel; Neem; Rashes; Turmeric