eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2024-03-30 21 1 267 272 10.13005/bbra/3223 50004 article Haneena 1 Neehara Bijal K 1 Aswin Krishna VV 1 Ahammed Shameem P 1 Thangamani S 1 Kiran DR 2 Department of Pharmacy Practice, Grace College of Pharmacy, Palakkad, Kerala, India. Background: Hypertension poses a serious threat to public health being a common and challenging condition to treat. The main cause of poor blood pressure regulation is non-adherence to treatment. Enhancing patient compliance and promoting preventative care are two benefits of pharmaceutical care based on patient education. Objective: The study was aimed to evaluate the therapeutic outcome of different class of antihypertensive after pre and post intervention in hypertensive patients and to evaluate whether patient participation in a pharmaceutical care program is associated with reduction in blood pressure. Method: A 6-month hospital based prospective interventional study was performed with 125 patients in the outpatient department of general medicine. The patients' medical records were reviewed and recorded the initial Blood pressure according to which pharmaceutical care intervention was performed which included verbal counselling, patient information leaflets, and patients were divided according to which they receive monotherapy and combination therapy then subsequent monitoring with two Follow-ups were carried out over a one-month interval and assessed the changes in Diastolic blood pressure and Systolic blood pressure. Result: Pharmaceutical care intervention provided to the patients, resulted in improvement in Blood pressure control knowledge and adherence to medication. Pharmaceutical care's impact on Systolic blood pressure and Diastolic blood pressure in patients undergoing monotherapy Angiotensin receptor blockers significantly reduced blood pressure readings, and in patients receiving combination therapy, angiotensin receptor blockers plus beta blockers significantly decreased systolic blood pressure while angiotensin receptor blockers plus calcium channel blockers significantly decreased diastolic blood pressure. Conclusion: Hypertensive patients who received pharmaceutical care reported better blood pressure management and overall patient satisfaction. https://www.biotech-asia.org/vol21no1/impact-of-pharmaceutical-care-interventions-on-clinical-outcome-in-patients-with-hypertension/ Blood pressure; Clinical outcome; Hypertension; Monotherapy; Pharmaceutical care