eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2024-03-30 21 1 69 79 10.13005/bbra/3203 49635 article Rajeev Ramachandra Kolgi 1 Bhargavi G 2 Nataraju Angaswamy 2 M V. Srinivasulu 3 Shankara Somashetty 4 Department of Chemistry and Biochemistry, Nrupathunga University, Bengaluru-01. Karnataka, India Department of Biochemistry, Karnataka State Open University, Mysuru-06. Karnataka, India Department of Botany, Nrupathunga University, Bengaluru-01. Karnataka, India Department of Microbiology, Nrupathunga University, Bengaluru-01. Karnataka, India Malignancy in the stomach is one of the silent causes of mortality due to a bad prognosis regardless of gender. It is the world's Fourth leading cause of death It is a disorder in which cancerous cells form in the stomach lining. The primary relationships begin between its carcinogenic route and Helicobacter pylori infection, following inflammation, and tissue regeneration. The review aims to evaluate biochemistry related to gastric cancer which focuses on cancer research including etiology, molecular basis, malignant transformation, tumor markers, prognosis, advancements in gastric (stomach) cancer and its therapeutics. The study of prognosis and advancements in gastric cancer helps a researcher, medical practitioner, or surgeon to develop safe, minimally invasive, and effective methods to prevent, screen, diagnose, and treat gastric cancer. https://www.biotech-asia.org/vol21no1/a-short-review-biochemical-aspects-and-advancements-in-gastric-cancer/ Adenocarcinoma; Chemotherapy; Etiology; Gastric Cancer; Helicobacter Pylori; Tumor Markers