eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2023-12-31 20 4 1249 1260 10.13005/bbra/3172 49066 article Sreedevi Sarsan 1 Puppala Harshanya 2 Sunkara Anika 2 Hesham Ali El Enshasy 3 R Z Sayyed 5 Department of Microbiology, St. Pious X Degree and PG College for Women, Hyderabad, Telangana, India Department of MBA, St. Pious X PG (MBA) College for Women, Hyderabad, Telangana, India Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), Skudai, Johor Bahru 81310, Malaysia City of Scientific Research and Technology Applications, New Burg Al-Arab, Alexandria 21934, Egypt Department of Microbiology, PSGVP Mandal's, S I Patil Arts, G B Patel Science and STKV Sangh Commerce College, Shahada 425409, India Faculty of Health and Life Sciences, INTI International University, Persiaran Perdana BBN, Putra Nilai, 71800 Nilai, Negeri Sembilan, Malaysia COVID-19 is a pandemic caused by SARS-CoV-2 – 2 that caused a devastating impact and has affected human population globally. The mitigation measures to impede and contain the spread of the COVID-19 disease included lockdowns, social distancing, and use of masks, hand sanitization & other basic hygiene practices. Administration of vaccines was considered the most effective strategy to reduce the risk of the disease. Several vaccines developed against multiple variants of Coronavirus to combat the dreadful disease. The project was taken with the objective to know the perceptions of people about the COVID-19 vaccines and was intended to evaluate the awareness, attitude, and factors determining their acceptance or hesitancy towards the vaccine among the Indian population. This study was conducted using a snowball sampling technique employing a cross-sectional and web-based online survey. A self-administered questionnaire was prepared and circulated among the general Indian population and feedback was collected and analyzed on knowledge and awareness, attitudes, and perceptions about COVID-19 vaccines. A total of 1,507 respondents from different states of India have participated in the survey. A considerable percentage of the population approximately 90% was fully vaccinated due to concerted efforts of Government authorities and health officials. The majority of the people were hesitant and unsure to administer booster doses of vaccines. The results suggested that the majority of the Indian population had good knowledge and awareness about Covid 19 vaccines and had a very positive attitude and acceptance towards vaccines but showed a lack of interest towards booster doses. Hence, various strategies need to be formulated to update the information to the public through awareness programs and their effective implementation. https://www.biotech-asia.org/vol20no4/acceptance-and-attitudes-towards-covid-19-vaccines-a-cross-sectional-study-from-india/ Acceptance; Attitudes; Booster Doses COVID-19; Coronavirus; Hesitancy; SARS-CoV – 2; Vaccines; India