eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-01-07 1 2 109 116 3401 article Waykar Bhalchandra 1 Department of Zoology, Reshtriya Arts, Science and Commerce College, Chalisgaon, District Jalgaon - 424 101 (India) Cypermethrin induced alternations in neuroendocrine cell of fresh water bivalve, parreysia cylindrical, has been studied after acute(0.499 ppm) upto 96 hours and chronic (0.0988 ppm) upto 21 days exposure. Pesticidal stress caused, vacuolization, acute cellular degeneration, clumping of chromatin material, undulation of cell envelope, damage of neuropile, pronounced alternation in C/N ratio, among the neurosectretory cells. In the initial stage of poisoning NSCs of cerebral, visceral and pedal ganglia showed decrease in C/N ratio after pesticidal stress indicating increased synthetic activity, this may be an initial response to the emergency caused by pesticidal stress. As the exposure period was increased, the C/N ratio was also increased, indicating decreased synthetic activity. Pesticidal stress, affected the pyriform cells [A-cells] as compare to oval cells [B-cells]. https://www.biotech-asia.org/vol1no2/cypermethrin-induced-alterations-in-neuroendocrine-cells-of-the-freshwater-bivalve-parreysia-cylindrica/ Cypermethrin; Neuroendrocrine; Parreysia cylindrica