eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2022-09-29 19 3 787 795 10.13005/bbra/3031 41565 article Venugopal N.V.S 1 Mohan Rao. G .N.V 1 Department of Chemistry, GITAM School of Science, GITAM(Deemed to be University ) Visakhapatnam-530045, A.P, India. In modern agriculture for receiving better crop yield and plant growth fertilizers are obligatory. Micronutrient support is very essential for  balanced crop nutrition. For elevated crop yield the optimal nutrient supply is very much necessary and it is possible only the presence of micronutrient matrix. Minute quantities of micronutrients are required for better physiology of plant kingdom. The purpose of the study was to formulate a new Nitrogen-Phosphorous-Potassium fertilizer with five micronutrients mould. The author developed  water soluble (100%) 15-15-15 grade fertilizer with 0.5%Zn,0.5%Mn,0.5%Fe, 0.5%Mg, 0.2%Mo as micronutrients support. The physical properties  such as moisture,pH,conductivity ,critical relative humidity etc were studied and found superior as compared to the normal grade without micronutrient support. The presence of Chloride content in the soil diminishes the capacity of the plants to take up water and this results in leaf burn or drying of leaf tissues. The chloride content in the proposed fertilizer is 0.27%. Nitrogen-Phosphorous-Potassium fertilizer fortified with five-micronutrient matrix and its application for finest Plant augmentation shown unsurpassed results and more crop yield. The proposed fertilizer with multi micronutrient matrix shown enhanced physical properties as compared to  available branded fertilizers. https://www.biotech-asia.org/vol19no3/formulation-development-and-characterization-of-an-eco-friendly-n-p-k-fertilizer-with-multi-micronutrient-matrix/ Critical relative humidity; Chloride Content; Micronutrient Matrix; N-P-K fertilizer; Plant growth