eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2019-09-25 16 3 669 679 10.13005/bbra/2782 34273 article Hala A. Abdolhaleem 1 Magda Abd Elaziz 2 Mostafa M. Bashandy 3 Wafai Z. A. Mikhail 4 Dairy Department, Food Technology Research Institute, Agricultural Research Center, Minisrty of agriculture, Giza, Egypt Dairy Chemistry Department., Animal production Research Institute, Agricultural Research Center, Minisrty of agriculture,Dokki -Giza, Egypt Clinical pathology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt Department of Natural Resources, Faculty of African Postgraduate Studies, Cairo University, Giza Egypt The present study was carried out to evaluate the efficiency of camel's milk to ameliorate the toxicity of aluminum chloride AlCl₃ on some hematological parameters; hepatic,renal functions andlipids profile; as well ashistopathological alterations of some organs. Forty rats (8 / group) were divided into 5 treatment groups:Group1: Normal rats (negative control); Group2: AlCl₃induced toxicity rats (positive control); Group3: AlCl₃induced toxicity rats fed with raw camel milk; Group4: AlCl₃ induced toxicity rats fed with heat treated camel milk; andGroup5: AlCl₃ induced toxicity rats fed with sweet acidophilus camel milk.Rats were treatedby 5ml camel’s milk 10 min before the administration of 1 ml AlCl₃ (0.5 mg / kgbody weight); and had their respective doses daily for 30 successive days orally. AlCl₃ oral administration resulted in a significant decrease in red blood cells count (RBC's), significant increase in mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH); while hemoglobin (Hb),  hematocrite (Hct),  platelets(plt),  reticulocytes (Ret), mean corpuscular hemoglobin concentration (MCHC) did not revealed significant changes; the obtained anemia was macrocytic normochromic. The lipids profile; hepatic and renal functions showed non significant changes between different groups; however, histopathological examination showed variable alterations of varying severity in some organs; besides their response to camel's milk administration. Camel’s milk administration in groups 3, 4, 5 alleviated the toxic effect of AlCl₃ with variable degrees between different groups. https://www.biotech-asia.org/vol16no3/impact-of-camels-milk-on-aluminum-chloride-alcl3-induced-toxicity-in-rats/ Aluminum Chloride; Camel's Milk; Kidney And Liver Functions; Lipids Profile; Macrocytic Normochromic Anemia; Red Blood Cells