eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2017-03-25 14 1 89 92 10.13005/bbra/2421 22451 article Оksana A. Voronina 1 Marina S. Tsarkova 1 Sergei Yu. Zaitsev 2 Federal State Budgetary Educational Institution of Higher Education “Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Skryabin”, Akad. Skryabin 23, Moscow, 109472 Russia. Biochemistry Department, Federal State Budgetary Educational Institution of Higher Professional Education “Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Skryabin”, Ministry of Agriculture of the Russian Federation, Akad. Scryabin Str. 23, Moscow, 109472 Russia. The information about the metabolic changes in animal body is very important and usually obtained by biochemical analysis of cow blood. A surface tension measurement of the cow serum is a modern analytical approach for the preliminary assessment of biochemical blood composition. In turn, a feeding is one of the factors determining the physiological-biochemical status of the animal. The two animal groups: 1) on “summer” diet (with “green-grass” nutrients); 2) on “winter” diet (with “silage and the concentrate” nutrients) were formed in order to estimate the influence of the animal diet on the physiological-biochemical status. Both diets were balanced by nutrients and energy. The influence of “summer” or “winter” diet on such metabolic parameters as glucose, cholesterol, triglycerides, total protein and albumin fractions at the level of 10-20% was found by biochemical analysis of the cow blood. The difference between these groups at the level of mineral metabolism was minimal. The study assessed the reliability of the application of the biochemical method and measurements of surface tension of cow blood as the comprehensive assessment of the impact of diet on physiological-biochemical status of the lactating cows. https://www.biotech-asia.org/vol14no1/nutrition-influence-on-blood-colloid-and-biochemistry-parameters-of-the-lactating-cow/ Biochemical analysis; biological active substances. Cow blood; Surface tension;Serum.Veterinary diagnostics;