eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2016-03-31 13 1 155 162 10.13005/bbra/2018 7476 article Alsheikh A. A 1 Mohammed W. S. 1 Noureldin E. M. 1 Daffalla O. M. 1 Shrwani K. J 1 Hobani Y. A. 1 National center for vector-borne diseases, Jazan 45142, Saudi Arabia. College of public health and tropical medicine, Jazan University. Saudi Arabia. Malaria program director, MoH- Riyadh, Saudi Arabia Minister Deputy for public health, MoH-Riyadh, Saudi Arabia. The present study was designed to provide information on the susceptibility status of the adult and larvae of Aedes aegypti mosquitoes in Jazan region of Saudi Arabia. Bioassay tests were performed on adults and larvae by using WHO recommended concentrations and test kits.  Adults of Ae. aegypti mosquitoes were exposed to test papers impregnated with Lambda-cyhalothrin (0.05%), Cyfluthrin (0.15%), Deltamethrin (0.05%), Permethrin (0.75%), Fenitrothion (1%), Bendiocarb (0.1%)  and DDT (4%) insecticides. Ae. aegypti mosquitoes were found to be susceptible only to Cyfluthrin; (mortality rate was 100 %), whereas variable resistances were observed from the rest of the other insecticides tested (mortality rates ranged between 93.6 and 17%). Larvae were subjected to different concentrations of Diflubenzuron, Methoprene (IGRs) and Temephos (Organophosphate). The inhibition of adult emergence (IE₅₀ and IE₉₅) values for the IGRs and the (LC₅₀ and LC₉₅) for Temephos have been determined by log-probit regression analysis. The Ae.aegypti larvae were resistant to Temephos (LC₅₀ 61.8 - LC₉₅ 35600.1 mg/l) and showed high susceptibility to Methoprene than Diflubenzuron (IE₅₀ 0.49 - IE₉₅ 10.9 mg/l) and (IE₅₀ 0.86 and IE₉₅ 93.8 mg/l), respectively. The larvae were more susceptible to Methoprene than Diflubenzuron by 1.8 folds. https://www.biotech-asia.org/vol13no1/resistance-status-of-aedes-aegypti-to-insecticides-in-the-jazan-region-of-saudi-arabia/ Insecticides; resistance; Aedes aegypti; Jazan region; Saudi Arabia