eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2015-08-15 12 2 1251 1254 2755 article Dehghani Naeimeh 1 Daneshpazhouh Hamed 1 Asmariansheyda 2 Shafiei Jahromi Nazanin 3 Poorgholami Farzad 4 Department of Biology,Payame Noor University ,19395-4697 ,Tehran, I. R. of Iran Department of Basic Science, Faculty of Veterinary Medicin, Kazerun Branch, Islamic Azad University, Kazerun, Iran. Department of Nursing, Islamic Azad University, Firuzabad Branch, Firuzabad, Iran. Reaserch center for non-Communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran. Diabet is one of the most disorders in endocrine part of pancreas. use some plants whit therapeutic effect such as lapa major is a route for remedy in diabet . this study was done to virify effect of root extract of lapa major. In this investigation 36 male vistrar rat were divided into 6 group randomly. Except for group 1, in all group diabet was induced .group 2 received insulin and in group 4,5 and 6 extract was administration in dose of 100, 200 and 300 mg/kg. blood samples were collected on day 7, 14 , and 21 .result were analyzed by anova test . results indicated that the level of blood glucose were increased after induced of diabet . the level of blood glucose in group which received insulin and in all diabetic groups in day 21 decresed signhficantly . in the other groups (4, 5) the level of glucose decreased , but not significantly . insupoosed that, because of low number of cases or low number of days that extract was administration. https://www.biotech-asia.org/vol12no2/antidiabetic-effect-of-burdock-tuber-arctiumlappa-l-extract-on-aloxan-diabetic/ Antidiabetic; Arctiumlappa L.; ethanolic extract