Natural strains of plant beneficial fungi Beauveria bassiana, Arthrobotrys oligospora and Duddingtonia flagrans showed in vitro antifungal activity against the Siberian strains of Fusarium oxysporum, Botrytis cinerea and Rhizoctonia solani phytopathogenic fungi. Adding entomopathogenic and nematophagous fungi to Bacillus amyloliquefaciens antagonistic bacterium increases its activity against plant pathogens. The results are promising for biocontrol of plant noxious organisms association in vivo.