This study was conducted to determine the effect of food safety knowledge level among high school students on their attitude to the subject. A total of 912 high school students between 15 and 17 years of age were included in the study and data was collected through questionnaires. The majority of those included in the study were male (70.4 %). The food safety knowledge level of females (=15.59±4.52) was found to be higher than that of males (=10.90±5.01). Similarly, the attitude scores of females were found to be higher in comparison with male participants (=46.67±5.98 and 43.53±7.03, respectively). A statistically significant difference between the genders in knowledge and attitude scores was found (p<0.001). There was also a positive relationship between food safety knowledge level and attitude (r=0.240, p<0.01).