eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2014-08-28 11 1 10356 article T. Lakshmi 1 R. Rajendran 1 Vijay Raghavan 1 Antony Silvester 1 Department of Pharmacology, Saveetha Dental College & Hospitals,Chennai, India. Green Chem Herbal Extracts and Formulations, Bangalore, India. To establish the fingerprint profile of total extract of Caralluma fimbriata using high performance thin layer chromatography (HPTLC) technique. HPTLC studies were carried out. CAMAG HPTLC system equipped with Linomat V applicator, TLC scanner 3, Reprostar 3 and WIN CATS-4 software were used. HPTLC finger printing of Caralluma fimbriata leaf extract revealed that the chromatogram obtained with the reference solution shows in the middle part a Dark blue zone [Slimalumaside A] at RF 0.33 and in the upper part a Blue zone [Slimalumaside B] at RF 0.94 was observed. It can be concluded that HPTLC fingerprint analysis of total extract of Caralluma fimbriata can be used as a diagnostic tool for the appropriate identification various extracts. https://www.biotech-asia.org/vol11no2/hptlc-fingerprinting-method-to-distinguish-total-extract-of-caralluma-fimbriata-from-the-modified-extracts-of-caralluma-fimbriata/ Caralluma adscendens var. fimbriata; HPTLC