eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2014-04-28 11 1 6175 article A. Julius 1 Rajalakshmi Allen 2 K. Pramila 3 A. Venkatesan 4 Bhuminathan Swamikannu 5 Department of Biochemistry, Shree Balaji Dental College and Hospital, Bharath University, Narayanapuram, Pallikaranai, Chennai- 600 100, India. Research and Development Department, Bharathiar University, Coimbatore, India. Department of Biochemistry, Prince Sri Venkateshwara Arts and Science College, Venkateshwara Nagar, Gowrivakkam, Chennai - 600073, India. Eshwar medical Foundation, Kolathur, Chennai, India. Department of Prosthodontics, Shree Balaji Dental College and Hospital, Bharath University, Narayanapuram, Pallikaranai, Chennai- 600 100, India. Objective is to study if there is any clinically signiûcant difference between EDTA plasma and serum for glucose and cholesterol estimation. A general problem faced by the clinical laboratories is the integrity of uncentrifuged specimens for chemical analyses. Because prolonged contact of plasma or serum with cell is a common cause of spurious test results, plasma and serum should ideally be separated from cells as quickly as possible to prevent ongoing metabolism of cellular constituents as well as active and passive movement of analytes between the plasma or serum and cellular compartments. (Goodman JR, Vincent J 1954). https://www.biotech-asia.org/vol11no1/comparitive-study-on-the-effect-of-serum-and-plasma-on-glucose-and-cholesterol-estimation/ Serum glucose; Plasma glucose; Serum cholesterol; Plasma cholesterol; EDTA plasma