eng Oriental Scientific Publishing Company Biosciences Biotechnology Research Asia 0973-1245 2013-12-28 10 2 10891 article M.N. Abubacker 1 T. Deepalakshmi 2 Department of Biotechnology, National College, Tiruchirappalli - 620 001, India. Department of Botany, National College, Tiruchirappalli - 620 001, India. Annona muricata Linn. (Soursop) of Annonaceae is a medicinal plant. Major bioactive compound methyl ester of hexadecanoic acid was isolated from the leaves. It was tested for antifungal potentials and found to be highly effective at 10.0, 15.0 mg/ml concentrations for Alternaria solani (NCBT-118) and Aspergillus erithrocephalus (NCBT-124); at 15.0 mg/ml concentration Aspergillus albicans (NCBT-120); less effective for Aspergillus fumigatus (NCBT-126) and Penicillium chrysogenum (NCBT 162). This bioactive compound will find a place in the formulation of herbal based antifungal drugs for the test fungi of this work. https://www.biotech-asia.org/vol10no2/in-vitro-antifungal-potentials-of-bioactive-compound-methyl-ester-of-hexadecanoic-acid-isolated-from-annona-muricata-linn-annonaceae-leaves/ Bioactive compound; Methyl ester of hexadecanoic acid; GC-MS analysis