Volume 3, number 2
 Views: (Visited 52 times, 1 visits today)    PDF Downloads: 187

Joseph N. M, Palani S, Verma N, Reddy A. Formulation Of Omeprazole Niosomes And Its Characterization. Biosci Biotechnol Res Asia 2005;3(2)
Manuscript received on : 21/11/2005
Manuscript accepted on : 
Published online on:  29-01-2016
How to Cite    |   Publication History    |   PlumX Article Matrix

Formulation Of Omeprazole Niosomes And Its Characterization

Nisha Mary Joseph, S. Palani, Navneet Verma and Amarnath Reddy

Department of pharmaceutics, Institute of Pharmacy, Bundelkhand University, Jhansi (India)

ABSTRACT: In the present study an attempt has been made to prepare niosomes. The niosomes formulation has got various advantages over conventional dosage form; these persist in the blood for a longer time than conventional and can thus greatly improve the therapeutic effect of drug. The niosomes are prepared by Reverse phase evaporation technique using a homogenizer. Omeprazole was selected as candidate drug, since it has been one of the major antacid and antiulcer agents used in the treatment of various types of diseases associated with GIT. Niosomes are characterized for its size range, entrapment efficiency and invitro release of drug. For release study the phosphate buffer saline pH 8.6 was used and the samples were assayed spectrophotometrically at 306 nm. The data obtained proved that the formulation was useful for the controlled release of drug because percentage release after 24 hours was nearly to 100%.

KEYWORDS: Omeprazole; in vitro study; entrapment efficiency

Download this article as: 
Copy the following to cite this article:

Joseph N. M, Palani S, Verma N, Reddy A. Formulation Of Omeprazole Niosomes And Its Characterization. Biosci Biotechnol Res Asia 2005;3(2)

Copy the following to cite this URL:

Joseph N. M, Palani S, Verma N, Reddy A. Formulation Of Omeprazole Niosomes And Its Characterization. Biosci Biotechnol Res Asia 2005;3(2). Available from: http://www.biotech-asia.org/?p=5439

(Visited 52 times, 1 visits today)

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.